Effect of pentoxifylline in reducing oxidative stress-induced embryotoxicity
نویسندگان
چکیده
منابع مشابه
Effect of pentoxifylline in reducing oxidative stress-induced embryotoxicity1
Purpose : To 1) evaluate the embryotoxic effects of hydrogen peroxide on mouse embryo development and 2) examine if pentoxifylline can reverse hydrogen peroxide induced embryotoxicity. Methods : Prospective in vitro study examining the effects of varying concentrations of hydrogen peroxide and pentoxifylline on the blastocyst development rate alone as well as in combination. Results : A dose-de...
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Objective Methotrexate (MTX), as an anti-folate agent, is widely used in the treatment of rheumatic disorders and malignant tumors, however it damages reproductive system in mice. The aim of this research was to study the effects of ethyl pyruvate (EP) on embryo development and oxidative stress changes in the testis of mice treated with MTX. MaterialsAndMethods In this experimental study, thirt...
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چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولPentoxifylline Attenuates Malathion-Induced Oxidative Damage in Rat
Introduction: Toxic effects of pesticides are commonly associated with reactive oxygen species damage and pentoxifylline a phosphodiesterase inhibitor is a drug well known for antioxidant properties. The purpose of this study was to evaluate the oxidative damages following a subacute exposure to malathion, an organophosphorus insecticide and pentoxifylline's ability to counteract these effect...
متن کاملRelationship between oxidative stress and embryotoxicity of hydrosalpingeal fluid.
BACKGROUND Oxidative stress mechanisms are involved in the pathophysiology of many reproductive disorders. The objective of this study was to characterize oxidative stress parameters in hydrosalpingeal fluid (HSF) and examine their possible role in early embryo development. METHODS AND RESULTS HSF was aspirated at laparoscopic salpingectomy in 11 infertile women. Reactive oxygen species (ROS)...
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ژورنال
عنوان ژورنال: Journal of Assisted Reproduction and Genetics
سال: 2005
ISSN: 1058-0468,1573-7330
DOI: 10.1007/s10815-005-7202-6